BAIT
PAICS
ADE2, ADE2H1, AIRC, PAIS
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
GO Process (5)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
SUPT5H
SPT5, SPT5H, Tat-CT1
suppressor of Ty 5 homolog (S. cerevisiae)
GO Process (16)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- 7-methylguanosine mRNA capping [TAS]
- DNA-templated transcription, elongation [IDA]
- cell cycle [NAS]
- chromatin remodeling [NAS]
- gene expression [TAS]
- negative regulation of DNA-templated transcription, elongation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of DNA-templated transcription, elongation [IDA]
- positive regulation of macroautophagy [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of viral transcription [TAS]
- response to organic substance [TAS]
- single stranded viral RNA replication via double stranded DNA intermediate [NAS]
- transcription elongation from RNA polymerase II promoter [IDA, TAS]
- transcription from RNA polymerase II promoter [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- DSIF complex [IDA]
- nucleoplasm [IDA, TAS]
- nucleus [IDA]
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]
Throughput
- High Throughput
Ontology Terms
- hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID