BAIT
TWF2
A6RP, A6r, PTK9L, MSTP011
twinfilin actin-binding protein 2
GO Process (10)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- barbed-end actin filament capping [ISS]
- cellular response to growth factor stimulus [IMP]
- cellular response to retinoic acid [IMP]
- negative regulation of actin filament polymerization [ISS]
- positive regulation of axon extension [IMP]
- positive regulation of lamellipodium assembly [IMP]
- positive regulation of neuron projection development [IMP]
- regulation of actin cytoskeleton organization [IMP]
- regulation of microvillus length [IC]
- sequestering of actin monomers [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TBCB
CG22, CKAP1, CKAPI
tubulin folding cofactor B
GO Process (2)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]
Throughput
- High Throughput
Ontology Terms
- cell line: hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID