ATG7
Gene Ontology Biological Process
- C-terminal protein lipidation [IBA]
- cellular protein modification process [TAS]
- cellular response to hyperoxia [IDA]
- cellular response to nitrogen starvation [IBA]
- cellular response to starvation [IDA]
- late nucleophagy [IBA]
- membrane fusion [TAS]
- mitochondrion degradation [IBA]
- piecemeal microautophagy of nucleus [IBA]
- positive regulation of apoptotic process [IMP]
- positive regulation of autophagy [IMP]
- positive regulation of macroautophagy [IMP]
- positive regulation of protein catabolic process [IMP]
- positive regulation of protein modification process [IDA]
- protein catabolic process [IBA]
- protein lipidation [IDA]
- protein modification by small protein conjugation [IBA]
Gene Ontology Molecular Function
TBCD
Gene Ontology Biological Process
- 'de novo' posttranslational protein folding [TAS]
- adherens junction assembly [IBA, ISS]
- cellular protein metabolic process [TAS]
- negative regulation of cell-substrate adhesion [ISS]
- negative regulation of microtubule polymerization [IDA]
- positive regulation of GTPase activity [IDA, IMP]
- post-chaperonin tubulin folding pathway [IDA]
- protein folding [IDA, TAS]
- tight junction assembly [IBA, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Throughput
- High Throughput
Ontology Terms
- hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ATG7 TBCD | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.5858 | BioGRID | 3223287 |
Curated By
- BioGRID