BAIT
P3H1
GROS1, LEPRE1, OI8, PSEC0109
prolyl 3-hydroxylase 1
GO Process (11)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- bone development [IMP]
- chaperone-mediated protein folding [ISS]
- collagen metabolic process [ISS]
- extracellular matrix organization [TAS]
- negative regulation of cell proliferation [NAS]
- negative regulation of post-translational protein modification [IMP]
- peptidyl-proline hydroxylation [ISS]
- protein folding [IMP]
- protein hydroxylation [IMP]
- protein stabilization [IMP]
- regulation of protein secretion [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
UBE3A
ANCR, AS, E6-AP, EPVE6AP, HPVE6A
ubiquitin protein ligase E3A
GO Process (9)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- androgen receptor signaling pathway [IBA]
- brain development [TAS]
- protein K48-linked ubiquitination [IDA]
- protein autoubiquitination [IDA]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IBA]
- proteolysis [TAS]
- regulation of circadian rhythm [IMP]
- regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process [IMP]
- ubiquitin-dependent protein catabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]
Throughput
- High Throughput
Ontology Terms
- hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID