BAIT
PDE4B
DPDE4, PDEIVB, RP5-876C12.1
phosphodiesterase 4B, cAMP-specific
GO Process (13)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- T cell receptor signaling pathway [IMP]
- cAMP catabolic process [IDA, IGI]
- cellular response to drug [ISS]
- cellular response to epinephrine stimulus [ISS]
- cellular response to lipopolysaccharide [ISS]
- leukocyte migration [ISS]
- negative regulation of relaxation of cardiac muscle [ISS]
- neutrophil chemotaxis [ISS]
- neutrophil homeostasis [ISS]
- positive regulation of interferon-gamma production [IMP]
- positive regulation of interleukin-2 production [IMP]
- regulation of cardiac muscle cell contraction [ISS]
- regulation of high voltage-gated calcium channel activity [ISS]
Gene Ontology Molecular Function
Homo sapiens
PREY
RCBTB2
CHC1L, RLG
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
GO Process (1)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
Increased risk for autism spectrum disorders (ASD) is attributed to hundreds of genetic loci. The convergence of ASD variants have been investigated using various approaches, including protein interactions extracted from the published literature. However, these datasets are frequently incomplete, carry biases and are limited to interactions of a single splicing isoform, which may not be expressed in the disease-relevant tissue. ... [more]
Nat Commun Apr. 12, 2014; 5(0);3650 [Pubmed: 24722188]
Throughput
- High Throughput
Curated By
- BioGRID