SIT4
Gene Ontology Biological Process
- DNA repair [IMP]
- G1/S transition of mitotic cell cycle [IGI]
- TOR signaling [IMP]
- actin cytoskeleton organization [IMP]
- cellular response to oxidative stress [IMP]
- dephosphorylation [IMP]
- fungal-type cell wall organization [IMP]
- intracellular signal transduction [IMP]
- replicative cell aging [IMP]
- tRNA wobble uridine modification [IMP]
Gene Ontology Molecular Function
SSD1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Dosage Rescue
A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene.
Publication
A general suppressor of RNA polymerase I, II and III mutations in Saccharomyces cerevisiae.
A multicopy genomic library of Saccharomyces cerevisiae (strain FL100) was screened for its ability to suppress conditionally defective mutations altering the 31 kDa subunit (rpc31-236) or the 53 kDa subunit (rpc53-254/424) of RNA polymerase III. In addition to allele-specific suppressors, we identified seven suppressor clones that acted on both mutations and also suppressed several other conditional mutations defective in RNA ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: temperature sensitive growth (APO:0000092)
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SSD1 SIT4 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 158947 | |
SIT4 SSD1 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 437261 | |
SIT4 SSD1 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 160270 |
Curated By
- BioGRID