FAM63B
Gene Ontology Cellular Component
CYP2J2
Gene Ontology Biological Process
- arachidonic acid metabolic process [TAS]
- epoxygenase P450 pathway [IDA, TAS]
- exogenous drug catabolic process [IBA]
- icosanoid metabolic process [TAS]
- linoleic acid metabolic process [IDA]
- oxidation-reduction process [IBA]
- regulation of heart contraction [TAS]
- small molecule metabolic process [TAS]
- xenobiotic metabolic process [TAS]
Gene Ontology Molecular Function- arachidonic acid 11,12-epoxygenase activity [IDA]
- arachidonic acid 14,15-epoxygenase activity [IDA]
- arachidonic acid epoxygenase activity [IDA]
- heme binding [IBA]
- linoleic acid epoxygenase activity [IDA]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [IBA]
- oxygen binding [IBA]
- steroid hydroxylase activity [IBA]
- arachidonic acid 11,12-epoxygenase activity [IDA]
- arachidonic acid 14,15-epoxygenase activity [IDA]
- arachidonic acid epoxygenase activity [IDA]
- heme binding [IBA]
- linoleic acid epoxygenase activity [IDA]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen [IBA]
- oxygen binding [IBA]
- steroid hydroxylase activity [IBA]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Quantitative Score
- 0.999999771 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.999999771, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FAM63B CYP2J2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 1193066 | |
| FAM63B CYP2J2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3143917 |
Curated By
- BioGRID