CD209
Gene Ontology Biological Process
- antigen processing and presentation [NAS]
- cell-cell recognition [TAS]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [TAS]
- intracellular signal transduction [NAS]
- intracellular transport of virus [TAS]
- leukocyte cell-cell adhesion [NAS]
- modulation by virus of host morphology or physiology [TAS]
- peptide antigen transport [NAS]
- regulation of T cell proliferation [IDA]
- viral genome replication [NAS]
- virion attachment to host cell [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
HTR1B
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [TAS]
- adenylate cyclase-inhibiting serotonin receptor signaling pathway [IDA]
- cellular response to alkaloid [IDA]
- cellular response to drug [IDA]
- negative regulation of cAMP biosynthetic process [IDA]
- negative regulation of serotonin secretion [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Quantitative Score
- 0.999614359 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.999614359, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CD209 HTR1B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9817 | BioGRID | 1190413 | |
| CD209 HTR1B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9986 | BioGRID | 3049693 |
Curated By
- BioGRID