BAIT

SXL

CG14425, CG18350, CG33070, CG43770, DmSxl, Dmel\CG43770, Dmel_CG14425, Dmel_CG18350, Fl, Mex156, ORF2, Su(da), Sx1, Sxl-1 Sxl-2, SxlPe, SxlPm, dSXL, fs(1)K1274, fs(1)M106, l(1)6Fa, melSxl, Dmel_CG43770
Sex lethal
Drosophila melanogaster

Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Functioning of the Drosophila integral U1/U2 protein Snf independent of U1 and U2 small nuclear ribonucleoprotein particles is revealed by snf(+) gene dose effects.

Cline TW, Rudner DZ, Barbash DA, Bell M, Vutien R

Snf, encoded by sans fille, is the Drosophila homolog of mammalian U1A and U2B" and is an integral component of U1 and U2 small nuclear ribonucleoprotein particles (snRNPs). Surprisingly, changes in the level of this housekeeping protein can specifically affect autoregulatory activity of the RNA-binding protein Sex-lethal (Sxl) in an action that we infer must be physically separate from Snf's ... [more]

Proc. Natl. Acad. Sci. U.S.A. Dec. 07, 1999; 96(25);14451-8 [Pubmed: 10588726]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
SXL TRA
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Low-FlyBase
-
SXL TRA
Affinity Capture-RNA
Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Low-FlyBase
-
SXL TRA
Phenotypic Suppression
Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Low-FlyBase
-
SXL TRA
Phenotypic Suppression
Phenotypic Suppression

A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Low-FlyBase
-
SXL TRA
Protein-RNA
Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Low-FlyBase
-

Curated By