BAIT
DAPK1
DAPK
death-associated protein kinase 1
GO Process (12)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [IGI, IMP, TAS]
- apoptotic signaling pathway [IMP]
- cellular response to interferon-gamma [IDA]
- intracellular signal transduction [IDA]
- negative regulation of translation [IDA]
- positive regulation of apoptotic process [TAS]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- protein autophosphorylation [IDA, TAS]
- protein phosphorylation [IDA, TAS]
- regulation of N-methyl-D-aspartate selective glutamate receptor activity [ISS]
- regulation of apoptotic process [IBA, TAS]
- regulation of autophagy [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LIMA1
EPLIN, SREBP3, PP624
LIM domain and actin binding 1
GO Process (3)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.
Signal transduction cascades governed by kinases and GTPases are a critical component of the command and control of cellular processes, with the precise outcome partly determined by direct protein-protein interactions (PPIs). Here, we use the human ROCO proteins as a model for investigating PPI signaling events-taking advantage of the unique dual kinase/GTPase activities and scaffolding properties of these multidomain proteins. ... [more]
Proteomics May. 01, 2018; 18(10);e1700444 [Pubmed: 29513927]
Throughput
- High Throughput
Additional Notes
- Significant hits in the protein microarray had a Z-score threshold of Z > 3.
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
DAPK1 LIMA1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 2754 | BioGRID | 3482850 |
Curated By
- BioGRID