BAIT

RPS6KA1

HU-1, MAPKAPK1A, RSK, RSK1, p90Rsk, RP11-492M19.2
ribosomal protein S6 kinase, 90kDa, polypeptide 1
GO Process (26)
GO Function (4)
GO Component (4)

Gene Ontology Cellular Component

Homo sapiens
PREY

GORASP1

GOLPH5, GRASP65, P65
golgi reassembly stacking protein 1, 65kDa
GO Process (3)
GO Function (0)
GO Component (2)
Homo sapiens

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

Gogl G, Biri-Kovacs B, Durbesson F, Jane P, Nomine Y, Kostmann C, Bilics V, Simon M, Remenyi A, Vincentelli R, Trave G, Nyitray L

Phosphorylation of short linear peptide motifs is a widespread process for the dynamic regulation of protein-protein interactions. However, the global impact of phosphorylation events on the protein-protein interactome is rarely addressed. The disordered C-terminal tail of ribosomal S6 kinase 1 (RSK1) binds to PDZ domain-containing scaffold proteins, and it harbors a phosphorylatable PDZ-binding motif (PBM) responsive to epidermal growth factor ... [more]

J. Mol. Biol. Mar. 15, 2019; 431(6);1234-1249 [Pubmed: 30726710]

Throughput

  • Low Throughput

Additional Notes

  • phosphorylated Rsk1

Curated By

  • BioGRID