BAIT
LAMTOR5
HBXIP, XIP
late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
GO Process (8)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- cellular response to amino acid stimulus [IMP]
- negative regulation of apoptotic process [IDA]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- positive regulation of GTPase activity [IDA]
- positive regulation of TOR signaling [IMP]
- protein localization to lysosome [IMP]
- regulation of cell size [IMP]
- response to virus [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
AKR1C2
AKR1C-pseudo, BABP, DD, DD-2, DD/BABP, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8, TDD
aldo-keto reductase family 1, member C2
GO Process (13)
GO Function (7)
GO Component (0)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA]
- cellular response to jasmonic acid stimulus [IDA]
- cellular response to prostaglandin D stimulus [IDA]
- daunorubicin metabolic process [IMP]
- digestion [IDA]
- doxorubicin metabolic process [IMP]
- epithelial cell differentiation [IEP]
- oxidation-reduction process [IDA]
- positive regulation of cell proliferation [IDA]
- positive regulation of protein kinase B signaling [IDA]
- progesterone metabolic process [IDA]
- prostaglandin metabolic process [IDA]
- steroid metabolic process [IDA]
Gene Ontology Molecular Function- alditol:NADP+ 1-oxidoreductase activity [IDA]
- bile acid binding [IDA]
- carboxylic acid binding [IDA]
- ketosteroid monooxygenase activity [IDA]
- oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [IDA]
- phenanthrene 9,10-monooxygenase activity [IDA]
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [IDA]
- alditol:NADP+ 1-oxidoreductase activity [IDA]
- bile acid binding [IDA]
- carboxylic acid binding [IDA]
- ketosteroid monooxygenase activity [IDA]
- oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [IDA]
- phenanthrene 9,10-monooxygenase activity [IDA]
- trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity [IDA]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.
The complexity of the skeletal muscle and the identification of numerous human disease-causing mutations in its constitutive proteins make it an interesting tissue for proteomic studies aimed at understanding functional relationships of interacting proteins in both health and diseases.We undertook a large-scale study using two-hybrid screens and a human skeletal-muscle cDNA library to establish a proteome-scale map of protein-protein interactions ... [more]
Skelet Muscle Feb. 19, 2013; 3(1);3 [Pubmed: 23414517]
Throughput
- High Throughput
Curated By
- BioGRID