CPA
Gene Ontology Biological Process
- actin cytoskeleton organization [IMP, NAS]
- actin filament organization [IMP]
- barbed-end actin filament capping [IMP, ISS, NAS]
- cell morphogenesis [IMP]
- germarium-derived oocyte fate determination [IMP]
- microtubule-based movement [ISS]
- negative regulation of JNK cascade [IGI]
- negative regulation of actin filament polymerization [IMP]
- negative regulation of filopodium assembly [IMP]
- phagocytosis [IMP]
- regulation of filopodium assembly [IMP]
- regulation of lamellipodium assembly [IMP]
- wing disc development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CPB
Gene Ontology Biological Process
- actin cytoskeleton organization [IMP]
- actin filament organization [IMP]
- barbed-end actin filament capping [IDA, IMP]
- border follicle cell migration [IMP]
- cell morphogenesis [IMP]
- cytoplasmic transport, nurse cell to oocyte [IMP]
- negative regulation of JNK cascade [IGI]
- negative regulation of filopodium assembly [IMP]
- positive regulation of synaptic growth at neuromuscular junction [IMP]
- regulation of actin filament length [IMP]
- regulation of lamellipodium assembly [IMP]
- wing disc development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
CPB CPA | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID