CPB
Gene Ontology Biological Process
- actin cytoskeleton organization [IMP]
- actin filament organization [IMP]
- barbed-end actin filament capping [IDA, IMP]
- border follicle cell migration [IMP]
- cell morphogenesis [IMP]
- cytoplasmic transport, nurse cell to oocyte [IMP]
- negative regulation of JNK cascade [IGI]
- negative regulation of filopodium assembly [IMP]
- positive regulation of synaptic growth at neuromuscular junction [IMP]
- regulation of actin filament length [IMP]
- regulation of lamellipodium assembly [IMP]
- wing disc development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CPA
Gene Ontology Biological Process
- actin cytoskeleton organization [IMP, NAS]
- actin filament organization [IMP]
- barbed-end actin filament capping [IMP, ISS, NAS]
- cell morphogenesis [IMP]
- germarium-derived oocyte fate determination [IMP]
- microtubule-based movement [ISS]
- negative regulation of JNK cascade [IGI]
- negative regulation of actin filament polymerization [IMP]
- negative regulation of filopodium assembly [IMP]
- phagocytosis [IMP]
- regulation of filopodium assembly [IMP]
- regulation of lamellipodium assembly [IMP]
- wing disc development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A protein complex network of Drosophila melanogaster.
Determining the composition of protein complexes is an essential step toward understanding the cell as an integrated system. Using coaffinity purification coupled to mass spectrometry analysis, we examined protein associations involving nearly 5,000 individual, FLAG-HA epitope-tagged Drosophila proteins. Stringent analysis of these data, based on a statistical framework designed to define individual protein-protein interactions, led to the generation of a ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CPA CPB | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
| CPA CPB | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 3712638 | |
| CPB CPA | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 3712649 |
Curated By
- BioGRID