CSNK1D
Gene Ontology Biological Process
- DNA repair [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- circadian regulation of gene expression [ISS]
- endocytosis [IBA]
- mitotic cell cycle [TAS]
- peptidyl-serine phosphorylation [IBA]
- positive regulation of canonical Wnt signaling pathway [IMP]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- positive regulation of protein phosphorylation [IMP]
- protein phosphorylation [IDA]
- regulation of cell shape [IBA]
- regulation of circadian rhythm [ISS]
- signal transduction [TAS]
- spindle assembly [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FAM83D
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.
Dynamic changes in protein-protein interaction (PPI) networks underlie all physiological cellular functions and drive devastating human diseases. Profiling PPI networks can, therefore, provide critical insight into disease mechanisms and identify new drug targets. Kinases are regulatory nodes in many PPI networks; yet, facile methods to systematically study kinase interactome dynamics are lacking. We describe kinobead competition and correlation analysis (kiCCA), ... [more]
Quantitative Score
- 0.603103085 [kiCCA Pearson R Value]
Throughput
- High Throughput
Additional Notes
- A kinobead competition and correlation analysis (kiCCA) involving a quantitative mass spectrometry-based chemoproteomic method was carried out to identify endogenous kinase interactors.
- High confidence interactions had a kiCCA Pearson R Value >=0.6.
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
CSNK1D FAM83D | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 238 | BioGRID | 3482269 | |
CSNK1D FAM83D | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9477 | BioGRID | 2252194 | |
CSNK1D FAM83D | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9562 | BioGRID | 3034224 |
Curated By
- BioGRID