BAIT

CTNNBL1

C20orf33, NAP, P14L, PP8304, dJ633O20.1, RP5-1118M15.1
catenin, beta like 1
GO Process (2)
GO Function (2)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

HSPA4

APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY
heat shock 70kDa protein 4
GO Process (3)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

CTNNBL1 is a novel NLS-binding protein that recognizes RNA splicing factors CDC5L and PRP31.

Ganesh K, Adam S, Taylor B, Simpson P, Rada C, Neuberger M

Nuclear proteins typically contain short stretches of basic amino acids (nuclear-localisation sequences; NLSs) which bind karyopherin α family members, directing nuclear import. Here we identify CTNNBL1 (catenin-β-like 1), an armadillo-motif-containing nuclear protein that exhibits no detectable primary sequence homology to karyopherin α, as a novel, selective NLS-binding protein. CTNNBL1 (a single-copy gene conserved from fission yeast to man) was previously ... [more]

Unknown Mar. 08, 2011; 0(0); [Pubmed: 21385873]

Throughput

  • Low Throughput

Curated By

  • BioGRID