LQF
Gene Ontology Biological Process
- autophagy [IDA]
- endocytosis [IMP, NAS, TAS]
- negative regulation of cardioblast cell fate specification [IMP]
- neurotransmitter secretion [NAS]
- positive regulation of Notch signaling pathway [IMP]
- regulation of Notch signaling pathway [IMP]
- storage protein import into fat body [IDA]
- synaptic vesicle endocytosis [NAS]
FAF
Gene Ontology Biological Process
- cellularization [IMP]
- compound eye development [IMP]
- defense response to Gram-negative bacterium [IMP]
- dorsal/ventral axis specification [IGI, IMP]
- embryo development [IMP]
- endocytosis [NAS]
- germ cell migration [TAS]
- mystery cell differentiation [IMP, TAS]
- negative regulation of innate immune response [IMP]
- negative regulation of proteolysis [NAS]
- nuclear migration [IMP]
- protein deubiquitination [IDA, IMP, NAS, TAS]
- ubiquitin-dependent protein catabolic process [IGI]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
A specific protein substrate for a deubiquitinating enzyme: Liquid facets is the substrate of Fat facets.
Eukaryotic genomes encode large families of deubiquitinating enzymes (DUBs). Genetic data suggest that Fat facets (Faf), a Drosophila DUB essential for patterning the compound eye, might have a novel regulatory function; Faf might reverse the ubiquitination of a specific substrate, thereby preventing proteasomal degradation of that protein. Additional genetic data implicate Liquid facets (Lqf), a homolog of the vertebrate endocytic ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FAF LQF | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| FAF LQF | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| FAF LQF | Phenotypic Suppression Phenotypic Suppression A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - |
Curated By
- BioGRID