USF1
Gene Ontology Biological Process
- carbon catabolite regulation of transcription [TAS]
- cellular response to insulin stimulus [IDA]
- glucose homeostasis [TAS]
- late viral transcription [IDA]
- lipid homeostasis [ISS]
- negative regulation of fibrinolysis [IC]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase II promoter by glucose [IMP, ISS]
- regulation of transcription from RNA polymerase II promoter [TAS]
- regulation of transcription from RNA polymerase II promoter by glucose [IC]
- response to UV [ISS]
- response to hypoxia [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA, IMP]
- bHLH transcription factor binding [IPI]
- enzyme binding [IPI]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IPI, TAS]
- protein kinase binding [IPI]
- sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA, IMP]
- bHLH transcription factor binding [IPI]
- enzyme binding [IPI]
- histone deacetylase binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IPI, TAS]
- protein kinase binding [IPI]
- sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
HCFC1
Gene Ontology Biological Process
- chromatin organization [TAS]
- histone H4-K16 acetylation [IDA]
- histone H4-K5 acetylation [IDA]
- histone H4-K8 acetylation [IDA]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of cell cycle [TAS]
- positive regulation of gene expression [IDA]
- protein stabilization [IDA]
- regulation of protein complex assembly [IDA]
- regulation of transcription, DNA-templated [IDA]
- release from viral latency [NAS]
- transcription from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function- chromatin binding [IDA]
- histone acetyltransferase activity (H4-K16 specific) [IDA]
- histone acetyltransferase activity (H4-K5 specific) [IDA]
- histone acetyltransferase activity (H4-K8 specific) [IDA]
- identical protein binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription coactivator activity [IMP]
- chromatin binding [IDA]
- histone acetyltransferase activity (H4-K16 specific) [IDA]
- histone acetyltransferase activity (H4-K5 specific) [IDA]
- histone acetyltransferase activity (H4-K8 specific) [IDA]
- identical protein binding [IPI]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription coactivator activity [IMP]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.
Chromatin insulators protect erythroid genes from being silenced during erythropoiesis, and the disruption of barrier insulator function in erythroid membrane gene loci results in mild or severe anemia. We showed previously that the USF1/2-bound 5'HS4 insulator mediates chromatin barrier activity in the erythroid-specific chicken β-globin locus. It is currently not known how insulators establish such a barrier. To understand the ... [more]
Throughput
- Low Throughput
Additional Notes
- figure 1A.
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
USF1 HCFC1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID