ELAVL1
Gene Ontology Biological Process
Gene Ontology Molecular Function
PTGS2
Gene Ontology Biological Process
- arachidonic acid metabolic process [TAS]
- cellular component movement [TAS]
- cellular response to hypoxia [IEP]
- cyclooxygenase pathway [IDA, TAS]
- lipoxygenase pathway [TAS]
- positive regulation of brown fat cell differentiation [ISS]
- positive regulation of cell migration involved in sprouting angiogenesis [ISS]
- positive regulation of fever generation [ISS]
- positive regulation of fibroblast growth factor production [ISS]
- positive regulation of nitric oxide biosynthetic process [ISS]
- positive regulation of platelet-derived growth factor production [ISS]
- positive regulation of prostaglandin biosynthetic process [NAS]
- positive regulation of transforming growth factor beta production [ISS]
- positive regulation vascular endothelial growth factor production [ISS]
- prostaglandin biosynthetic process [ISS, NAS]
- prostaglandin metabolic process [TAS]
- regulation of blood pressure [ISS]
- regulation of inflammatory response [NAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells.
RNA-binding proteins regulate multiple steps of RNA metabolism through both dynamic and combined binding. In addition to its crucial roles in cell adhesion and Wnt-activated transcription in cancer cells, β-catenin regulates RNA alternative splicing and stability possibly by binding to target RNA in cells. An RNA aptamer was selected for specific binding to β-catenin to address RNA recognition by β-catenin ... [more]
Throughput
- Low Throughput
Additional Notes
- surface plasmon resonance analysis of binding to fragments from the PTGS2 3' UTR
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ELAVL1 PTGS2 | Affinity Capture-RNA Affinity Capture-RNA An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis. | Low | - | BioGRID | 905206 | |
| ELAVL1 PTGS2 | Protein-RNA Protein-RNA An interaction is detected between and protein and an RNA in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID