BAIT
ERP44
PDIA10, TXNDC4, UNQ532/PRO1075
endoplasmic reticulum protein 44
GO Process (5)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PAK2
PAK65, PAKgamma
p21 protein (Cdc42/Rac)-activated kinase 2
GO Process (24)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- T cell costimulation [TAS]
- T cell receptor signaling pathway [TAS]
- apoptotic process [TAS]
- axon guidance [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- innate immune response [TAS]
- intracellular signal transduction [IBA]
- mitotic cell cycle [IBA]
- negative regulation of apoptotic process [IMP, TAS]
- negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis [IDA]
- negative regulation of protein kinase activity [TAS]
- peptidyl-serine phosphorylation [IDA]
- phosphorylation [IDA]
- positive regulation of extrinsic apoptotic signaling pathway [IMP]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of protein tyrosine kinase activity [IDA]
- protein autophosphorylation [IDA]
- protein phosphorylation [IDA]
- regulation of apoptotic process [TAS]
- regulation of defense response to virus by virus [TAS]
- signal transduction [TAS]
- signal transduction by phosphorylation [IBA]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]
Throughput
- High Throughput
Ontology Terms
- cell line: hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID