BAIT
YWHAB
GW128, HEL-S-1, HS1, KCIP-1, YWHAA, RP1-148E22.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
GO Process (22)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- MAPK cascade [TAS]
- RNA metabolic process [TAS]
- Ras protein signal transduction [TAS]
- activation of MAPKK activity [TAS]
- apoptotic process [TAS]
- axon guidance [TAS]
- cytoplasmic sequestering of protein [IDA]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [TAS]
- gene expression [TAS]
- hippo signaling [TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- intrinsic apoptotic signaling pathway [TAS]
- mRNA metabolic process [TAS]
- membrane organization [TAS]
- negative regulation of protein dephosphorylation [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of catalytic activity [IDA]
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [TAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC9A3R1
EBP50, NHERF, NHERF-1, NHERF1, NPHLOP2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
GO Process (14)
GO Function (9)
GO Component (13)
Gene Ontology Biological Process
- bile acid secretion [ISS]
- glutathione transport [ISS]
- microvillus assembly [IMP]
- negative regulation of ERK1 and ERK2 cascade [IDA]
- negative regulation of cell proliferation [IDA, IMP]
- negative regulation of phosphatidylinositol 3-kinase signaling [ISS]
- negative regulation of platelet-derived growth factor receptor signaling pathway [ISS]
- negative regulation of protein kinase B signaling [IMP]
- positive regulation of intrinsic apoptotic signaling pathway [IDA]
- protein complex assembly [TAS]
- regulation of protein kinase activity [ISS]
- regulation of sodium:proton antiporter activity [NAS]
- renal absorption [ISS]
- renal phosphate ion absorption [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A high-throughput approach for measuring temporal changes in the interactome.
Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]
Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]
Throughput
- High Throughput
Ontology Terms
- hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID