BAIT

LDHB

HEL-S-281, LDH-B, LDH-H, LDHBD, TRG-5

lactate dehydrogenase B

GO Process (3)

GO Function (1)

GO Component (4)

Gene Ontology Biological Process

cellular metabolic process [TAS]

pyruvate metabolic process [TAS]

small molecule metabolic process [TAS]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA, TAS]

extracellular vesicular exosome [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

YWHAB

GW128, HEL-S-1, HS1, KCIP-1, YWHAA, RP1-148E22.1

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

GO Process (22)

GO Function (6)

GO Component (7)

Gene Ontology Biological Process

Fc-epsilon receptor signaling pathway [TAS]

MAPK cascade [TAS]

RNA metabolic process [TAS]

Ras protein signal transduction [TAS]

activation of MAPKK activity [TAS]

apoptotic process [TAS]

axon guidance [TAS]

cytoplasmic sequestering of protein [IDA]

epidermal growth factor receptor signaling pathway [TAS]

fibroblast growth factor receptor signaling pathway [TAS]

gene expression [TAS]

hippo signaling [TAS]

innate immune response [TAS]

insulin receptor signaling pathway [TAS]

intrinsic apoptotic signaling pathway [TAS]

mRNA metabolic process [TAS]

membrane organization [TAS]

negative regulation of protein dephosphorylation [IDA]

neurotrophin TRK receptor signaling pathway [TAS]

positive regulation of catalytic activity [IDA]

positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [TAS]

small GTPase mediated signal transduction [TAS]

Gene Ontology Molecular Function

enzyme binding [IPI]
histone deacetylase binding [IPI]
phosphoprotein binding [IPI]
phosphoserine binding [IPI]
protein binding [IPI]
protein domain specific binding [IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

cytoplasmic vesicle membrane [TAS]

extracellular vesicular exosome [IDA]

focal adhesion [IDA]

perinuclear region of cytoplasm [IDA]

CRISPR Database VEGA OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

A high-throughput approach for measuring temporal changes in the interactome.

Kristensen AR, Gsponer J, Foster LJ

Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches, but these methods do not provide stoichiometric or temporal information. We combine quantitative proteomics and size-exclusion chromatography to map 291 coeluting complexes. This method allows mapping of an interactome to the same depth and accuracy as AP-MS with less work and without overexpression or tagging. The use ... [more]

Nat. Methods Sep. 01, 2012; 9(9);907-9 [Pubmed: 22863883]

Throughput

High Throughput

Ontology Terms

hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
LDHB YWHAB	Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.	Moutaoufik MT (2019)	High	1.6641	BioGRID	2629120

Curated By

BioGRID