AURKB
Gene Ontology Biological Process
- abscission [ISS]
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [TAS]
- attachment of spindle microtubules to kinetochore [TAS]
- cellular response to UV [IDA]
- cleavage furrow formation [IDA]
- cytokinesis checkpoint [ISS]
- histone H3-S28 phosphorylation [ISS]
- histone modification [TAS]
- mitotic cell cycle [TAS]
- mitotic spindle midzone assembly [IMP, TAS]
- negative regulation of B cell apoptotic process [IDA]
- negative regulation of cytokinesis [ISS]
- negative regulation of protein binding [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of cytokinesis [IMP, TAS]
- protein autophosphorylation [TAS]
- protein localization to kinetochore [IMP]
- protein phosphorylation [IDA]
- regulation of chromosome segregation [TAS]
- spindle stabilization [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
HSP90AB1
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- axon guidance [TAS]
- innate immune response [TAS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [TAS]
- positive regulation of nitric oxide biosynthetic process [ISS]
- regulation of interferon-gamma-mediated signaling pathway [IMP]
- regulation of type I interferon-mediated signaling pathway [IMP]
- response to unfolded protein [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.
Centrosome morphology and number are frequently deregulated in cancer cells. Here, to identify factors that are functionally relevant for centrosome abnormalities in cancer cells, we established a protein-interaction network around 23 centrosomal and cell-cycle regulatory proteins, selecting the interacting proteins that are deregulated in cancer for further studies. One of these components, LGALS3BP, is a centriole- and basal body-associated protein ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| AURKB HSP90AB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 56.8438 | BioGRID | 3485802 | |
| AURKB HSP90AB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| AURKB HSP90AB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8561 | BioGRID | 1198155 | |
| AURKB HSP90AB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.878 | BioGRID | 2261335 | |
| AURKB HSP90AB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID