CHI
Gene Ontology Biological Process
- axon guidance [IMP]
- blastoderm segmentation [TAS]
- chaeta development [IMP]
- chaeta morphogenesis [IMP]
- compound eye development [IMP]
- dendrite guidance [IMP]
- imaginal disc-derived wing morphogenesis [IMP]
- nervous system development [IMP]
- phagocytosis [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- regulation of eclosion [IMP]
- regulation of gene expression [IMP]
- transcription, DNA-templated [IMP]
Gene Ontology Molecular Function
AP
Gene Ontology Biological Process
- axon guidance [IMP]
- cell fate commitment [NAS]
- dorsal/ventral lineage restriction, imaginal disc [TAS]
- dorsal/ventral pattern formation, imaginal disc [TAS]
- haltere disc morphogenesis [NAS]
- histolysis [IMP]
- imaginal disc-derived leg segmentation [IMP]
- imaginal disc-derived wing morphogenesis [TAS]
- larval somatic muscle development [IMP]
- leg disc development [IMP]
- leg disc proximal/distal pattern formation [IMP]
- muscle organ development [IMP, TAS]
- nervous system development [IMP, TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- transcription, DNA-templated [IMP, TAS]
- wing disc dorsal/ventral pattern formation [IGI, IMP, TAS]
- wing disc morphogenesis [NAS]
Gene Ontology Molecular Function
Phenotypic Suppression
A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
The level of DLDB/CHIP controls the activity of the LIM homeodomain protein apterous: evidence for a functional tetramer complex in vivo.
The LIM homeodomain (LIM-HD) protein Apterous (Ap) and its cofactor DLDB/CHIP control dorso- ventral (D/V) patterning and growth of Drosophila wing. To investigate the molecular mechanisms of Ap/CHIP function we altered their relative levels of expression and generated mutants in the LIM1, LIM2 and HD domains of Ap, as well as in the LIM-interacting and self-association domains of CHIP. Using ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CHI AP | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | FlyBase | - | |
| AP CHI | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| CHI AP | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| CHI AP | Phenotypic Suppression Phenotypic Suppression A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| CHI AP | Phenotypic Suppression Phenotypic Suppression A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| CHI AP | Phenotypic Suppression Phenotypic Suppression A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| CHI AP | Phenotypic Suppression Phenotypic Suppression A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | FlyBase | - | |
| CHI AP | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - | |
| CHI AP | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | FlyBase | - |