BTG1
Gene Ontology Biological Process
- cell migration [NAS]
- negative regulation of cell growth [NAS]
- negative regulation of cell proliferation [IDA]
- positive regulation of angiogenesis [IMP]
- positive regulation of endothelial cell differentiation [IMP]
- positive regulation of fibroblast apoptotic process [IMP]
- positive regulation of myoblast differentiation [IDA, NAS]
- regulation of transcription, DNA-templated [NAS]
Gene Ontology Molecular Function
PRMT1
Gene Ontology Biological Process
- cell surface receptor signaling pathway [TAS]
- histone H4-R3 methylation [IDA]
- histone methylation [IDA]
- negative regulation of megakaryocyte differentiation [IDA]
- neuron projection development [IMP]
- peptidyl-arginine methylation [IDA]
- peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [IBA]
- protein methylation [TAS]
- regulation of transcription, DNA-templated [IBA]
Gene Ontology Molecular Function- N-methyltransferase activity [IDA, IMP]
- histone methyltransferase activity [IDA]
- histone methyltransferase activity (H4-R3 specific) [IDA]
- identical protein binding [IPI]
- methyltransferase activity [TAS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- protein-arginine omega-N asymmetric methyltransferase activity [IBA]
- N-methyltransferase activity [IDA, IMP]
- histone methyltransferase activity [IDA]
- histone methyltransferase activity (H4-R3 specific) [IDA]
- identical protein binding [IPI]
- methyltransferase activity [TAS]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- protein-arginine omega-N asymmetric methyltransferase activity [IBA]
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Interaction of PRMT1 with BTG/TOB proteins in cell signalling: molecular analysis and functional aspects.
BACKGROUND: Several recent reports have connected protein methylation with differentiation. Furthermore, the BTG/TOB proteins have also been implicated in such control. BTG1 and 2 have been shown to interact with PRMT1 (predominant cellular arginine N-methyltransferase of type I). RESULTS: First, we have studied the interaction between PRMT1 and the proteins of the BTG/TOB family. We show that boxC, a sequence ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PRMT1 BTG1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| BTG1 PRMT1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID